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How long can I take hydroxychloroquine? How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year.
Can discoid lupus be cured? There is no permanent cure for discoid lupus. Treatment aims to prevent new sores, limit scarring, and make the skin look healthier. Without treatment, a discoid lupus rash will often worsen. creams or ointments to be applied directly to affected areas of the skin.
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