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Mortality results from a randomized prostate-cancer screening trial.
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AR expression in the prostate epithelium of both untreated and bicalutamide-treated mice (Fig.
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In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.
It is used like chewing tobacco and is placed in the mouth, usually between the gum and cheek.
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Take Casodex (bicalutamide) exactly as prescribed.
Green stool is also common, especially after eating green or purple foods, However, green stool that continues for a longer time could actually be because of a medical problem.
It is used as a meat tenderizer in the food industry.
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When prostate cancer has spread to nearby tissues or metastasized to other areas in the body, treatment measures include androgen-deprivation therapy, chemotherapy, and biologic therapy.
CONTACT YOUR DOCTOR IMMEDIATELY if you experience black or bloody stools; blurred vision or other vision changes; bone pain; breast growth or pain; changes in the amount of urine produced; chest pain; dark or bloody urine; fainting; fever, chills, or persistent sore throat; flu-like symptoms; increased hunger, thirst, or urination; joint pain, stiffness, or swelling; loss of appetite; mental or mood changes (eg, anxiety, depression); muscle aches or weakness; numbness or tingling of the skin; pale stools; severe or persistent cough; severe or persistent dizziness, drowsiness, or headache; severe or persistent nausea or stomach pain; shortness of breath; swelling of the ankles, legs, or feet; unusual bruising or bleeding; unusual tiredness or weakness; vomiting; weight change; or yellowing of the skin or eyes.
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Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine.
In some cases, gynecomastia may be disturbing enough to cause men to discontinue therapy.
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Talk to your pediatrician regarding the use of this medicine in children.
New urine test for prostate cancer available; unlike PSA test, is ultra-specific for prostate cancer.
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Elevations in prolactin require evaluation for a tumor involving or impinging on the anterior pituitary or may indicate ingestion of various prescription or recreational drugs.
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Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, Yang H, Rochon J; Drug Induced Liver Injury Network (DILIN).
The Panel did not include the other treatment options in the analysis and recommendations due to a combination of factors, including limited published experience and short-term follow-up as well as the similar issues that affected evaluations of other treatment options (see the "Methodology" and the "Summary of Treatment Complications" sections for an explanation of data limitations).
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The measuring units used at your laboratory (Moffitt) to represent the testosterone are not typical.
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Process according to claim 1, characterised in that a recrystallisation of crude bicalutamide to give crystallised Bicalutamide from a crystallisation solvent chosen from ethyl acetate, methyl isobutyl ketone MIBK, acetonitrile, isopropyl alcohol, isobutyl alcohol, or 1-methoxy-2-propanol, possibly aqueous.
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Ketoconazole reduces androgen production in the testes and the adrenal glands.
In vitro studies have shown that R-bicalutamide is an inhibitor of CYP 3A4 with lesser inhibitory effects on CYP 2C9, 2C19 and 2D6 activity.
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Problems that are likely to arise in the disease management movement mirror difficulties that have surfaced in health maintenance organisations.
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Firstly the number of experimental and clinical studies remains relatively small and secondly they are often limited in terms of their quality (lack of adequate numbers to achieve statistical significance, lack of randomized controlled trials, and the findings that these compounds only appear to have marginal efficacy when assessed in head-to-head clinical trials).
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In pharmacology, bioavailability is a measurement of the rate and extent to which a drug reaches at the site of action.
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Healthcare institutions should initiate in-house disease management programmes that assist primary care physicians in doing a better job rather than outsourcing growing portions of health care to specialised commercial outfits.
And any time a woman feels concerned about signs or symptoms that arise after menopause, she should feel free to talk to her doctor, he said.
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There are different types of benign breast disease, including some types caused by an increase in the number of cells or by the growth of abnormal cells in the breast ducts or lobes.
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Medical Research Council Prostate Cancer Working Party Investigators Group.
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Objective tumor progression was defined as the appearance of any bone metastases or the worsening of any existing bone metastases on attributable to metastatic disease, or an increase by 25% or more of any existing measurable extraskeletal metastases.
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Although intermittent therapy may rely upon restoring a normal testosterone level, it is believed that the testosterone level should be as low as possible when the patient is on treatment, thus generating the lowest serum PSA level possible and likely improving outcome.
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