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The acclaimed drug, considered a magic bullet for leukemia, was actually developed jointly by Dr Brian Druker, director of the Oregon Health and Science University Knight Cancer Institute, in collaboration with Nicholas Lydon of Novartis.

However, the patents of all three products has expired as of 2014, and the company needs to rapidly expand and diversify its product offering.

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To improve the effectiveness of BNCT for malignant gliomas, we utilized epithermal neutron and two different boron compounds, sodium borocaptate (BSH) and boronophenylalanine (BPA) with different accumulation mechanisms to increase the boron level in tumors.

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Narayana Murthy, about 60 years of age, is from a small village called Narasipura, about 50 km from Shimoga in Karnataka.

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T1 MRIs were acquired immediately post-treatment to assess the extent of convection, and DWMRIs were acquired 24 h later to assess tissue response.

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To inhibit autophagy, HIV-1 lentivirus-based vectors were used to introduce shRNAs against ATG7 or Beclin-1 as already reported.

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