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Impact of Enzalutamide Compared with Bicalutamide on Quality of Life in Men with Metastatic Castration-resistant Prostate Cancer: Additional Analyses from the TERRAIN Randomised Clinical Trial.

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When more than one site of metastasis is present, the most advanced category should be used.

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Treatment with bicalutamide tablets should be started at the same time as treatment with an LHRH analog.

Back, pelvic, stomach, or general body pain; constipation; decreased sexual ability; diarrhea; dizziness; frequent urination, especially at night; gas; headache; hot flashes; nausea; stomach upset; sweating; trouble sleeping; weakness.

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Several case reports of (which may progress to ) in association with bicalutamide treatment have been published in the medical literature.

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Cryotherapy, also known as cryosurgery and cryoablation, can be an alternative to radical prostatectomy.

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What happens when Hormone Therapy stops in controlling the prostate cancer and it advances to soft tissues and other parts of body.

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In fact, since bicalutamide actually increases testosterone levels in males, the levels of these metabolites might be elevated similarly.

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Multicenter phase II study of combined neoadjuvant docetaxel and hormone therapy before radical prostatectomy for patients with high risk localized prostate cancer.

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Overview of the safety and side effects of the nonsteroidal antiandrogens; ALT elevations in 6% receiving bicalutamide vs 10% with flutamide; clinically apparent hepatitis can occur but is rare).

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Any condition or reason that, in the opinion of the Investigator, interferes with the ability of the patient to participate in the trial, which places the patient at undue risk, or complicates the interpretation of safety data.

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Are there any other tests that he should have?

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Treatment should be directed at correcting any underlying reversible causes.

Gleave et al showed a significant improvement with 8-month neoadjuvant therapy compared with 3 months.

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Central cicatricial centifugal alopecia (CCCA) is a form of traction alopecia caused by chemical relaxers, oils, gels, dyes and bleaches.

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Investigators and patients were informed of the results and patients had the option of breaking their blind and switching to bicalutamide as open-label therapy.

The lack of AR N- and C-terminal interaction in the bicalutamide-liganded AR is not surprising as this is mediated by an L XXLL-like motif in the N terminus and is dependent on an agonist conformation in the ligand binding domain ().

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However, if you're more comfortable with proceeding with therapy, I would go ahead with that as treatments do not always have major complications.

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Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telophase.

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Consideration should therefore be given to monitoring blood glucose in patients receiving bicalutamide in combination with LHRH agonists.

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Hepatic impairment (if transaminases increase over 2 times the upper limit of normal discontinue the treatment with this drug).

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The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle.

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The ancient theories of Chinese medicine suggest that Qi (a vital force or energy) flows through the body along channels called meridians.

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As more patients with advanced prostate cancers receive antiandrogen chemotherapy, more cases of drug-induced lung diseases may be encountered.

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