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No similar estimates are available for Loa loa-related events.
The availability of resources in turn depends on social stability, economic wealth, and priority allocation of resources to public health.
Adverse events were more common in the ivermectin group, but all events were mild and resolved quickly.
All drugs analysed in this study were obtained randomly from the main pharmacies within Nairobi in Kenya and Bukavu in the Democratic Republic of the Congo in 2004.
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Currently, more than 70 million treatments are approved for onchocerciasis in Africa and Latin America and 80 million for lymphatic filariasis in Africa and Yemen each year.
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Geneva World Health Organization 2001 Takougang I Meremikwu M Wandji S Yenshu EV Aripko B Lamlenn SB Eka BL Enyong P Meli J Kale O Remme JH Rapid assessment method for prevalence and intensity of Loa loa infection Bull World Health Org 2002 80 852 858 12481206 Murray CJL Lopez AD The Global Burden of Disease Cambridge Harvard University Press 1996 Chippaux JP Boussinesq M Gardon J Gardon-Wendel N Ernould JC Severe adverse reaction risks during mass treatment with ivermectin in loiasis-endemic areas Parasitol Today 1966 12 448 450 15275280 10.
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This applies to the use of chemical rotations or mixtures, which can be applied to give either moderation or saturation depending on the concentration and intensity of use.
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Assessment of immunochromatographic test for rapid lymphatic filariasis diagnosis.
Because such analysis is highly time-consuming - and because the results can vary significantly depending on details of the context - we generally do not provide cost-effectiveness analysis for an intervention unless we find what we consider to be a strong associated giving opportunity.
WHO confirms the potential for elimination of river blindness in some parts of Africa through current treatment strategies.
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Another subset of problematic infections is known as neglected tropical diseases (NTDs).
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Since absorbing the River Blindness Foundation in 1996, The Carter Center has assisted the ministries of health in the six Latin American countries, and in Africa assists Ethiopia, Nigeria, Sudan, and Uganda.
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Such interventions could build on the local infrastructure and experience gained, and may require the use of an agency such as the MDP, and the partnership mechanisms that have been employed.
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The Mectizan Donation Program displayed Merck's support of the stakeholder theory and that its duty lied with its patients.
Thus, REXULTI may be administered without dosage adjustment in these patients.
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In 2015 The Carter Center helped the Ministry of Health launch the Nigeria Onchocerciasis Elimination Committee.
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Through centralized fora like the (WHO), countries should clarify priorities for the global health agenda, allocate more attention to health-related needs, advocate for greater accountability among nongovernmental organizations, and improve the monitoring and evaluation of global health initiatives.
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This critical situation was compounded by the emigration of Ethiopia's skilled health professionals to other countries.
The extent to which the incidence of a disease is sensitive to a nominated change at a particular geographical location depends on the interaction of the disease organism, its vector, its host population, and the environment (Fig.
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While the disease is not a direct cause of mortality, the socioeconomic consequences of onchocerciasis are profound and extend beyond the individual, affecting families, communities, and countries as a whole.
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Cochrane review asserts that mass treatment with ivermectin has been shown to effectively and significantly reduce infection rates in flies and humans.
Effective Cure for River Blindness2.
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These infections often result in major socioeconomic liabilities, as working-aged adults are often the ones debilitated, leaving the young to care for the adults as well as to provide for the family.
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Gardon J, Boussinesq M, Kamgno J, Gardon-Wendel N, Demanga N, Duke BO: Effects of standard and high doses of ivermectin on adult worms of Onchocerca volvulus: a randomised controlled trial.
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Hopkins also served four years on the Technical Consultative Committee of APOC and has completed almost four years as chairperson of the NGDO coordination group for Onchocerciasis Control.
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Active community engagement and participation has successfully empowered communities to manage and supervise the distribution of the medicine, ivermectin to millions of people.
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They concluded that the now 17-year old Mectizan Donation Program is a successful and cost effective program for preventing the debilitating effects of river blindness.
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In Africa, where it was once thought the disease could only be controlled, strides are being made to completely eliminate the disease from a number of countries.
Ducorps M Gardon-Wendel N Ranque S Ndong W Boussinesq M Gardon J Schneider D Chippeaux J-P Effets secondaires du traitement de la loase hypermicrofilarémique par l'ivermectine Bulletin de la Societe de Pathologie Exotique et de ses Filiales 1995 88 105 112 Gardon J Gardon-Wendel N Demanga-Ngangue Kamgno J Chippaux J-P Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection Lancet 1997 350 18 22 9217715 10.
Our own pre-Civil War slavery laws, for example, required us to treat slaves like property, and the laws of Nazi Germany required anti- Semitic behavior.
Once these notions have been clarified, we devote the next chapter to a discussion of some basic theories of ethics and how they relate to business.
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We have not done thorough cost-effectiveness analysis of this program.
In 1998, the donation of Mectizan was expanded to include the treatment of lymphatic filariasis in those African countries where that disease is co-endemic with onchocerciasis.
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